Immunologist - Flow Cytometry & In Vivo Models

About Hooke

Hooke is a privately owned, founder-led preclinical CRO focused on rodent in vivo immunology, based in Lawrence, MA (relocating to Salem, NH in Q1 2027). We're the leading specialty CRO in our field, serving 8 of the top 10 global pharmas alongside biotechs, universities, and startups. See the "About the company" section below for more.

For all positions, Hooke offers:

• Health insurance
• Company contributions to HSA accounts
• Paid vacation
• 401(k) plan

About the Role

We are seeking an early-career PhD immunologist with strong expertise in flow cytometry. You will be working with rodent models of immune-mediated diseases.

What you will do

• Design, optimize, and run multi-color flow cytometry panels (including high-parameter/spectral systems)
• Operate spectral and polychromatic flow cytometers
• Analyze and interpret flow cytometric results from rodent and human tissues
• Integrate flow cytometry into in vivo study design and readouts
• Contribute to interpretation of results from models of autoimmune diseases (EAE, lupus, arthritis, etc.)
• Support preparation of clear, high-quality reports
• Help refine internal assays, panels, and scientific approaches

Requirements

• PhD in immunology (recent graduate to early-career)
• >>> Multi-color panel design
• >>> Compensation/unmixing
• >>> Data analysis (FlowJo or similar)
• Experience with high-parameter flow (>=12 colors); spectral cytometry is a strong plus
• Interest or experience in working hands-on with rodent models of immune-mediated diseases
• Excellent understanding of immune cell phenotyping
• Careful, detail-oriented approach to experimental design, study execution, and data analysis

Nice to have

• Experience with genomics and gene-editing techniques such as CRISPR-Cas9

To apply

• Email ***email_hidden*** (no calls, please)
• Attach your resume or CV in PDF format
• Include contact information for three references
• Put "IMMUNO_FLOW - [initials] [family name]" in the subject line